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These side effects may be more common after initiation and during dose escalation

Summary: GLP-1 receptor agonists are not licensed for anxiety treatment and lack established evidence for direct anxiolytic effects, though some patients may experience secondary psychological improvements through metabolic health gains

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But theres no clinical evidence that these patches actually work

It is also possible that there was more protein aggregation at pH 7 than pH 5 as previous research has shown that protein aggregates can form at neutral pH due to hydrophobic interactions, even if the isoelectric point is at a different pH (Vetri et al., 2007)