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El protocolo estndar recomienda comenzar con 0,25 mg semanales durante un mes, luego 0,5 mg el siguiente mes y, tras la evaluacin mdica, escalar hasta 1 mg o ms segn la respuesta clnica y la tolerancia
The post says an eGFR assessment is recommended before initiation, especially in older adults or people with diabetes, and it notes that both medications can influence fluid balance and renal perfusion
Diabetes Obes Metab 2009
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