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Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

A View Beyond HbA1c: Role of Continuous Glucose Monitoring

Because this detoxification pathway relies heavily on glutathione, a deficiency means that histamine remains circulating in the bloodstream for prolonged periods

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