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It is primarily done by using depigmenting topical creams or lotions with active components like hydroquinone, tretinoin, and corticosteroids

For these individuals, a supplement that works through different, gentler mechanisms may be worth trying

STEP 1 Trial (NEJM 2021) Semaglutide 2.4 mg achieved 14.9% mean body weight reduction vs 2.4% with placebo at 68 weeks

This can manifest as: reduced fetal movements and abnormal position in the uterus floppy appearance when held rare, weak cry poor sucking reflex

semaglutide for obesity, glycaemic control, and cardiovascular outcomes: a narrative review of clinical trials

This is particularly helpful for patients who have undergone bariatric surgery or lost massive amounts of weight