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SELECT Trial - New England Journal of Medicine : The pivotal trial demonstrating 20% cardiovascular event reduction with semaglutide in people with obesity but without diabetes, establishing the cardioprotective effect independent of glucose-lowering

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Other serious but rare risks include pancreatitis and gallbladder disease

For a 250-pound patient, that translates to roughly 37 pounds

While the primary use of Rybelsus is to treat type 2 diabetes by preventing the liver from making too much sugar and helping the pancreas to produce more insulin, many people use it to help promote weight loss

Prednisone and Alcohol Combining prednisone with alcohol can exacerbate the medication's side effects such as stomach irritation and ulcers