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42 In the STEP 1 study, participants who achieved a mean weight loss of 10.6% after 20 weeks of semaglutide were rerandomized in STEP 4 to either continue semaglutide or switch to placebo for an additional 48 weeks

Current frequently used GLP-1-based medications include: Ozempic (semaglutide) : A GLP-1 receptor agonist approved for type 2 diabetes management

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Cagrilintide dosing in combination trials starts at 0.3 mg once weekly and is titrated in stepwise increments up to 4.5 mg weekly based on tolerability and efficacy data from the CagriSema and related trials

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