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Lactate shuttle: from substance exchange to regulatory mechanism

Patients carrying the 'A' allele typically demonstrate more pronounced stomach-emptying delays, predisposing them to stronger and longer-lasting sulfur burps during initial therapy

Overall, 75% were White, 5% were Black or African American and 17% were Asian

In heterodimeric GST complexes such as those formed by the cytosolic mu and alpha classes, however, the cleft between the two subunits is home to an additional high-affinity nonsubstrate xenobiotic binding site, which may account for the enzymes' ability to form heterodimers