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Conditions like pernicious anaemia (an autoimmune condition affecting a protein called intrinsic factor vital for B12 absorption), stomach issues (such as from reduced stomach acid or certain medications like proton pump inhibitors), intestinal disorders (like Crohns disease or coeliac disease), or even surgical removal of parts of the small intestine (e.g., gastric bypass surgery) can prevent proper absorption

In controlled in vitro models, researchers may evaluate receptor binding dynamics, signal transduction responses, and peptide stability, particularly in relation to its modified structure and extended activity profile under defined experimental conditions

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Inspired by the structure of natural C c O, we demonstrated a biomimetic synthetic strategy for scalable synthesis of porous Fe-N 3 single-atom nanozymes using Hb as both template and Fe-source, which delivered a high oxidase-like activity