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Its overexpression is associated with a decrease in acquisition of MET, cyclin D1, and CDK4 (oncogene and cell cycle-related proteins), which eventually lead to are duction in cell growth and enhanced cell apoptosis in vitro and in vivo (Jiang et al., 2016)

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Pharmacies that rely on published literature or default USP guidelines usually assign shorter BUDs (14-28 days)

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While some researchers argue that HTN-CM is a distinct entity, others suggest it may represent the coexistence of hypertension with hypertrophic cardiomyopathy (HCM)