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They differ fundamentally in size, metal dependency, mechanism, and primary research applications
This paper reports the cryo-electron microscopy structure of the GSDMD pore and reveals its charge-based selectivity for releasing mature IL-1
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10.1007/s11357-014-9704-6 104 FoxN.BlackR.GilmanS.RossorM.GriffithS.JenkinsL.et al (2005)
Unlike systemic steroids or NSAIDs, BPC-157 does not impair immune function or elevate liver enzymes