Diabetes Treatment Originally, semaglutide was developed to treat Type 2 diabetes
In Phase II trials, MariTide demonstrated up to approximately 20% average weight loss at 52 weeks in people living with obesity or overweight, without evidence of a plateau, suggesting even greater results with longer treatment

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The percentage of adults achieving an HbA1c of less than 7% at 32 weeks was 89.3% in the combination therapy group, 69% in the semaglutide group and 33.3% in the cagrilintide group
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[37] There also may be differences in under reporting energy intake in individuals with obesity compared to those who are lean, as well as those who are actively losing weight compared to those who are maintaining