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Long-Term Peak Results: Brello cites studies indicating that maximum weight reduction requires long-term adherence

Two landmark trials for heart failure management and SGLTI2-i were EMPA-REDUCED (Empagliflozin Outcome Trial in Patients with Chronic Heart Failure and a Reduced Ejection Fraction) and EMPA-PRESERVED (Empagliflozin Outcome Trial in Patient with Chronic Heart Failure with Preserved Ejection Fraction)

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Evidence indicates that GLP-1RAs can reduce the occurrence of MI [70]

Furthermore, increased funding for Research and Development from AstraZeneca and Amgen indicates a commitment to innovation in this sector

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