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Collagen Increased collagen synthesis by GHK-Cu, superior to vitamin C (+50%) and retinol (+40%) in vitro

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For example: Around a strained Achilles tendon Near a rotator cuff injury SubQ in the abdomen for systemic inflammation Localized delivery may enhance growth factor expression and collagen synthesis directly at the site of damage

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In double-blind, placebo-controlled trials, daily application of GHK-Cu cream at 3% concentration for 12 weeks produced a 70% increase in skin collagen thickness as measured by ultrasound imaging, a 40% increase in skin elasticity, and visible reduction in fine lines and wrinkles