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Regulators warn of a growing "black market" But as demand accelerates, so too has the gray and black market

It is highly effective but operates through GLP-1 only, without GIP, glucagon, or IGF-1 receptor activation

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Semaglutide initially slows gastric emptying (an effect that may attenuate over time), meaning food remains in the stomach for longer periods, which promotes satiety and reduces hunger signals

Novo Nordisks Competitors The move also intensifies competition in the fast-growing GLP-1 market, where Novo Nordisk faces pressure from rival drugmaker Eli Lilly, which makes diabetes medication Mounjaro and weight-loss drug Zepbound