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It depends on the treatment sought and the patient's metabolism, which will determine the answer to this question

Although the enrichment of L-cells by pharmacological agents can be a novel approach for improving insulin secretion, glucose tolerance and the treatment of T2DM, more research for the specific differentiation of L-cells and the translation of in vitro and animal data to humans, are needed for the success of this approach

Unintentional weight loss exceeding clinical targets, inability to maintain adequate nutrition or hydration, or new or worsening heartburn or reflux symptoms that don't respond to over-the-counter treatments also warrant medical consultation

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G., & Van Hout, M

That is a 94% reduction in dead space loss