Yes, non-diabetic individuals tolerate GLP-1 medications well, with safety data from thousands of participants in clinical trials
In contrast, CCK, GIP, GLP-1, and PYY are predominately released postprandially and, in concert, mediate intestinal feedback to limit postprandial glycemic excursions and suppress energy intake (2, 3)
Semaglutide: A Strong Contender Wegovy, known generically as Semaglutide, has become widely recognized for its substantial efficacy in promoting weight loss
Iskandar, D
Preclinical studies using native GLP-1 or GLP-1RA have provided convincing evidence of its cardioprotective benefits, while clinical trials have shown positive effects on hypertension and dyslipidemia in patients with T2DM [3]
Combat it with: 25-35g fiber daily (vegetables, fruits, whole grains, legumes) 2-3+ liters of water daily Magnesium glycinate supplement (200-400mg before bed helps with both constipation and sleep) Carbs around training: Dont eliminate carbs