is retatrutide a triple agonist mechanism gip glp-1 glucagon receptor phase 2 trial obesity First-in-Class 'Triple-G'! Retatrutide in Johnson County Retatrutide vs Tirzepatide (Research Comparison)

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Acute peripheral administration of synthetic human GLP-1 (7-36 amide) decreases circulating IL-6 in obese patients with type 2 diabetes mellitus: a potential role for GLP-1 in modulation of the diabetic pro-inflammatory state

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These were generally consistent with the known side-effect profile of GLP-1 receptor agonists and were most frequently observed during the dose-escalation phase