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It does not establish that cagrilintides longer half-life means a better outcome half-life is pharmacokinetics, not efficacy

Needle size, for example, is exceedingly small, making subcutaneous administration at home relatively painless compared to larger needle gauges used with thicker medications for things like blood draws

These studies used doses ranging from 1 mg per day to 30 mg per day administered through various routes (subcutaneous, oral, and intranasal)

Compare week 12 with the week-0 baseline and week 6

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It is also an important thiol buffer, maintaining sulfhydryl groups in their reduced form, an additional mechanism for cellular signaling