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Morgan ET, Koop DR, Coon MJ: Comparison of six rabbit liver cytochrome P450 isozymes in formation of a reactive metabolite of acetaminophen

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After 18 h BSO and cysteine incubation, excess media was removed, replaced with 100 L A6 media containing 0.6 MOI frog virus 3 (FV3) (37), and incubated at 30C for 1 hour

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These findings suggest that APS may treat DR by modulating the SHH-Gli1-AQP1 signaling pathway, offering a novel therapeutic approach for DR