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User 15 cited a general dosing range of 2.5 to 3.75mcg per kilogram of body weight twice daily, which, at higher body weights, still produces doses within the standard 250 to 500mcg range being used across the dataset
p = 0.009
The hepatic enzyme inhibition may cause an additional increase in potency and a prolonged metabolic half-life (prolonged metabolic half-life for all ways of drug administration)
Waiting on the doctor frustrates patients and the team and negatively impacts revenue