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Descriptions range from icy hands and feet to a lingering, bone-deep freeze that hits unexpectedly and doesnt let up

Cagrilintide combined with semaglutide (CagriSema) represents the next generation of combination therapies

Moving forward requires transparency about what we know and what we dont, delivered with a heavy dose of humility and true empathy for the patients seeking answers

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Tirzepatide is not a hormone replacement therapy but influences metabolic hormones indirectly through its dual GIP/GLP-1 receptor actions, improving insulin secretion, reducing glucagon, and affecting appetite-regulating pathways