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There are other medications, like tirzepatide and liraglutide, that work in similar ways, and some drugs use totally different methods to help people lose weight

Prostate 2015;75(11):11771186

The FDA approval process requires extensive Phase I-III clinical trials demonstrating safety, efficacy, pharmacokinetics, and quality manufacturing standards

In other words, dead cells shed faster so newer cells come to the surface sooner

Serious adverse events occurred in 6.2% of patients in the liraglutide group and 5.0% in the placebo group

Those with pre-existing chronic liver disease warrant closer surveillance, though semaglutide is not contraindicated in compensated liver disease