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These individuals may require approximately 3045% weight loss to achieve a normal BMI

The infusion of this filtrate into the GI tract serves to counteract dysbiosis by directly replenishing a consortium of beneficial bacteria

This allows multiple withdrawals across weeks of treatment

As a result, in October 2023, the American Heart Association first proposed CKM syndrome, recognizing the interconnected pathophysiology and a series of common consequences, if left untreated or poorly managed, of these individual diseases

Can use together

However, patients in high-risk groups (over 60, concurrent metformin use, vegan diet, post-bariatric surgery) may benefit from additional supplementation