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GLP-1 agonists affect diverse obesity etiopathogenic processes such as abnormal food intake regulation, adipocyte dysfunction, insulin resistance, adipokine production, inflammation, endothelial dysfunction, lipid metabolism, and oxidative stress

Many individuals continue using supplements throughout their time on GLP-1 medications to help support hydration, protein intake, and overall nutrition consistency

2022 Feb;161(2):e91-e96

Countries in North America, particularly the US, have the highest rates of diabetes and obesity in the world

To date, only a few human ALS studies (referenced above) have identified specific systemic effectors

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