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Notably, reduced inflammation was accompanied by decreased glomerular hypertrophy, mesangial expansion and type IV collagen deposition
For the erosion index, six sites in the ankle joint were scored: the talus, navicular bone, medial cuneiform bone, and the bases of the first, second, and third metatarsals
This GLP-1 drug also reduces the risk of heart attack and stroke in people with diabetes and cardiovascular disease
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Pillar 6: Pioglitazone (PPAR-gamma agonist) Pioglitazone can improve insulin sensitivity partly by redistributing fat away from ectopic depots (liver and muscle) towards safer subcutaneous stores
Injectable tirzepatide has more clinical evidence demonstrating effectiveness
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