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Using forceps, the stimulus was applied to the rats hind limb by momentarily pinching the areas innervated by the tibial, fibular, and sural nerves

These pathways facilitate the production of energy in the form of adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide phosphate (NADPH), both of which are essential for numerous cellular reactions (34, 35)

These individuals may require closer monitoring and more aggressive preventive strategies

Regulatory and safety status: It is currently awaiting FDA review

There is no standardised list of side effects, no established safety profile, and no regulatory body monitoring adverse reactions