Treatment considerations include: Concurrent folate supplementation if deficient (never give folate alone, as it may precipitate neurological deterioration) Potassium monitoring during initial treatment in severe anaemia or at-risk patients (e.g., those with heart failure) Response assessment: reticulocyte count peaks at 57 days, haemoglobin normalises within 68 weeks Neurological symptoms may take 612 months to improve and may not fully resolve Patients should be advised that treatment for pernicious anaemia or post-surgical deficiency is lifelong
We also investigated the behavior of GSH(t) during the menstrual cycle, and showed that GSH remains stable during the menstrual cycle, which was completely unexpected given the wide range of GSH steady states seen in Figure 2
Neuropathology At the conclusion of the twelve-week (3 months) treatment period, mice were euthanized using CO 2 and tissues were collected and processed
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[79] References [edit] 1 2 3 4 5 "Optimal management of pernicious anemia"
Chen W, Wang Y, Pan Z, Chen X, Luo D, Wang H