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DOI: 10.1111/jocd.12910

The model is also consistent with published results that show that female mice are less susceptible than males to hepatotoxicity due to acetaminophen overdose and suggests that this might also be true for humans, though the human epidemiological data are contradictory

A pathological excess of ROS - as is associated with CYP induction (65), ultraviolet irradiation, xanthine oxidase activity under conditions of ischaemia-reperfusion, and so on - threatens cell viability by jettisoning just those homeostatic mechanisms that physiological oxidative stress secures (21)

However, many uncertified dermatologists recommend it in high doses via intravenous route

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