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If GI symptoms are still significant at the end of a four-week block, the documented approach is to hold the current dose longer rather than escalate on schedule

Thigh injections tend to absorb slightly slower than abdominal injections, which some researchers find helpful for managing initial side effects

typically require the disclosure of side effects

GI side effects: Continue to decrease over time

Combining PDE5 inhibitors or adding prostaglandin analogs can raise priapism risk and is generally discouraged unless under specialist supervision

Endogenous catecholamine synthesis, metabolism, storage and uptake in human neutrophils