The quasimesenchymal pancreatic ductal epithelial cell line PANC-1-A useful model to study clonal heterogeneity and EMT subtype shifting
Agarwal S, Sasane S, Kumar J, Deshmukh P, Bhayani H, Giri P, et al
Variability : Not everyone sees the same amount of improvement
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In animals, GSH synthesis is regulated by feedback inhibition based on cysteine availability and the balance between the catalytic and regulatory subunits of glutamate-cysteine ligase (GCL) (Yang et al., 2002)