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Safety endpoints were rare and not linked to GLP-1 RA use, except for diabetic retinopathy (aHR, 1.49
Caution is advised in patients with a history of pancreatitis, gallbladder disease, or severe gastrointestinal disorders such as gastroparesis
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They also act on appetite centres in the brain, reducing hunger and food intake
Kafri warns that not all compounded medications are safe, and those sourced from unregulated pharmacies can be harmful, posing risks to both health and treatment outcomes
The majority of patients are genuinely happy
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