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Ingredients: 2 cups arugula or dandelion greens 2 tbsp olive oil 2 cloves garlic, minced Optional: chili flakes Directions: Heat olive oil, saut garlic
In a retrospective analysis of 182 patients with MDS with various subtypes, the multivariate analysis revealed a significant benefit in OS for patients receiving ICT with 140.9 months vs 36.3 months (p=0.0008) in case of refractory anemia (RA or, according to the present WHO classification: MDS-RS), 133.4 months vs 73.3 months (p=0.02) in case of refractory anemia with ring sideroblasts (RARS/RARS-t, corresponding to MDS-RS according to the present WHO classification) and no difference for refractory cytopenia with multilineage dysplasia (RCMD/RCMD-RS, corresponding to MDS-MLD according to the present WHO classification) (146)
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5 Lower doses: Eight in ten real-world patients were on maintenance doses below 1.7 mg of semaglutide or 10 mg of tirzepatide
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AMs release fibrosis-associated cytokines such as TGF-1 and osteopontin (OPN), increase lysosomal membrane permeability, and promote the release of damage-associated molecular patterns (DAMPs), activating TLRs/NF-B, MAPKs, and other inflammatory signaling pathways (58, 109) (see Figure 4b)
