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MET-097i: Fully-biased GLP-1 receptor agonist utilizing HALO platform technology for ultra-long half-life (~380 hours)

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Behav Brain Res 207, 377386 (2010)

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DOSING USED IN PHASE 3 STUDIES In the most recent studies from the TRIUMPH programme (Phase 3) , retatrutide was administered as follows: Route: Subcutaneous Frequency: Once weekly Study duration: Approximately 68 weeks Recommended Dosage (Clinical Research Escalation Model) Retatrutide is administered once weekly using a gradual dose escalation to improve tolerability