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It is an active endocrine tissue that secretes pro-inflammatory signaling molecules, including interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hsCRP), into the circulation

Rotate injection sites: Alternate between thighs or arms to avoid irritation or scar tissue

You see the same percentage of lean mass loss, so that makes it, okay

COA / Lab results Evidence: Clinical trial Pros Triple GLP-1 / GIP / glucagon agonism in one peptide raises energy expenditure, not appetite alone Largest weight reduction reported for an incretin-class compound (~24% at 12 mg, 48-wk phase 2) Reductions in HbA1c, visceral fat and liver-fat content across trials Once-weekly subcutaneous dosing (albumin-bound half-life) Cons GI effects require gradual multi-week dose titration Newest of the GLP-1 class phase 3 (TRIUMPH) topline only

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