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ISBN 9781442564411

Side effects are typically mild and temporary, such as slight soreness at the injection site

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Despite the promising therapeutic potential of MSCs for PH, broader large-scale production and clinical application require addressing key challenges of MSCsincluding heterogeneity, tumorigenicity, reduced biological function, and senescence during in vitro culturethrough the following strategies: standardizing MSC preparation and enriching homogeneous subpopulations using flow cytometry and immunomagnetic bead sorting

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