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When symptoms are present, they can include fatigue and discomfort in the upper right side of your abdomen In very severe cases, as the condition progresses, you might experience: Jaundice (when your skin or the whites of your eyes turn yellow due to liver damage) Swelling in your abdomen or legs If fatty liver disease leads to cirrhosis, you might experience: Fatigue Weakness Nausea Loss of appetite Weight loss Swelling Jaundice Its unclear exactly what causes fatty liver disease when it isnt caused by alcohol