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Recent studies suggest that cancer cells are under increased oxidative stress caused by oncogenic transformation, leading to metabolic alterations that result in ROS production 56

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By scavenging reactive oxygen species (ROS) and enhancing endogenous antioxidant defenses, compounds such as curcumin, resveratrol, quercetin and EGCG activate cytoprotective pathways like Nrf2/ARE, improve mitochondrial function, and reduce oxidative stress-induced apoptosis in neuronal cells ( Current therapeutic options for PD such as levodopa/carbidopa, pramipexole, selegiline, entacapone, trihexyphenidyl and deep brain stimulation are often limited by high cost, restricted accessibility and significant adverse effects including hallucinations, impulse-control disorders, dyskinesias, hepatotoxicity and cognitive impairment as well as surgery-related complications

Most patients improve in 6-12 weeks with conservative care

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