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Discontinuation Due to AEs: GLP-1 RAs were associated with an increased risk of treatment discontinuation due to AEs

Fans had mixed reactions: one noted, "It's because you are 41

The frequency and dose flexibility of each option help users choose based on lifestyle and comfort

CagriSema (the cagrilintide plus semaglutide combination) has been filed for FDA review and could receive approval by late 2026 or early 2027

Supply shortages and availability Both tirzepatide and semaglutide have experienced supply disruptions, but at different times

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