Autism and mental retardation: Neuropathologic studies performed in four retarded persons with autistic behavior
& Valenti, P
When patients present with concerning symptoms whilst taking B12 supplements, alternative diagnoses should be considered, including allergic reactions to supplement excipients, interactions with other medications, or coincidental illness
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In the brain of children with ASD, low levels of mitochondrial glutathione, mitochondrial dysfunction, oxidative stress and oxidative damage to macromolecules such as lipids, proteins and DNA have been reported (James et al., 2009)
Shureiqi I, Jiang W, Zuo X, Wu Y, Stimmel JB, Leesnitzer LM, Morris JS, Fan H-Z, Fischer SM, Lippman SM (2003) The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells