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1 H NMR (400 MHz, DMSO) 8.72 (s, 1H), 8.25 (s, 1H), 8.02 (d, J = 8.3 Hz, 1H), 7.46 (d, J = 6.5 Hz, 9H), 7.14 (dd, J = 7.3, 2.5 Hz, 6H), 7.08 (s, 1H), 6.94 (t, J = 5.7 Hz, 1H), 6.75 (t, J = 5.8 Hz, 1H), 4.71 (s, 1H), 4.13 (td, J = 8.2, 5.2 Hz, 1H), 3.52 (d, J = 5.7 Hz, 2H), 3.07 (d, J = 14.8 Hz, 1H), 2.85 (dd, J = 16.6, 8.5 Hz, 3H), 1.35 (s, 24H)

In a subsequent study Ohnemus et al

As GLP-1 medications continue to evolve, I believe they will dramatically change not only aesthetics but also public health and longevity worldwide

Side-effects and possible issues with long-term use of these novel agents have yet to be fully evaluated

Acknowledgements This work was supported by the Medical Research Council [grant numbers MR/J01186X/1, G0901321, MR/M006301/1], (the third grant is a UK New Investigator Research Grant supporting MJB)

Prog Nucl Magn Reson Spectrosc