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This plays a role in its many functions

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doi:10.1001/archotol.1993.01880180068013

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The critical role of NAD + pool in tumorigenesis NAD + not only acts as a co-enzyme for metabolic redox reactions, but also functions as a co-substrate to modulate the activity of NAD + -consuming enzymes that govern the critical steps in tumorigenesis, including genome stability, metabolism, cell growth, cell death, redox homeostasis and immune response

Start with lower doses to assess tolerance and gradually increase over 2-3 weeks