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Because the compound lacks regulatory approval, any product marketed for human use is being sold through unofficial channels that do not meet pharmaceutical manufacturing standards, raising documented concerns about purity, composition, and contamination
Cardiovascular Outcome Trials of the Incretin-Based Therapies: What Do We Know So Far
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This is of particular concern given the European Medicines Agencys (EMA) recent alert regarding a possible link between GLP-1 receptor agonists and an increased risk of suicidal ideation and behavior ( In light of these concerns, this study aims to investigate the potential association between tirzepatide use and the risk of suicide in patients with obesity
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