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The inclusion of glucagon agonism is why retatrutide produces such dramatically different outcomes in liver fat reduction compared to GLP-1 only compounds
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It leads to stress-eating, skipped doctor visits, and avoidance of movement
Dr Nic Kormas is a Senior Staff Specialist Endocrinologist and Head of Department for the Endocrinology Service at Concord Hospital
Further, if the once-daily reformulation of danuglipron is unsuccessful, we would expect Pfizer to continue development with another GLP-1 drug sourced internally or acquired from one of the several smaller firms developing drugs within this mechanism of action
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