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Compounds that can either stabilize NRF2 or inhibit KEAP1, thereby enhancing NRF2's antioxidative response, are under investigation for their potential neuroprotective effects against radiation-induced damage [41]

Beyond the regulatory picture, online forums and peptide communities frequently raise a structural argument about why human trials may never happen: BPC-157s amino acid sequence is in the public domain, which would make it difficult to patent and therefore commercially unattractive for a pharmaceutical company to fund through the expensive late-stage trial process

Boron could adsorb on MPs, because B(OH) 3 attaches to dissolved organic matter through surface complexations [53]

867 HSPA5, member A of the heat shock protein family, directly binds to GPX4 and positively regulates its expression