doi:10.1073/pnas.1521238113
Trials evaluating SS-31 for patients with heart failure or primary mitochondrial myopathies failed to show significant improvements on their primary endpoints
This gives you 5mg/ml, making dose math easy: 10 units = 0.5mg 20 units = 1.0mg 30 units = 1.5mg 10mg Vial Recommendation for 10mg vial: Add 2ml of BAC water
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Initial dosing starts at 200-300 mcg daily, administered subcutaneously, with gradual increases to therapeutic levels of 500-1000 mcg daily over 2-3 weeks