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Oftentimes, too-high levels of oxidative stress and Glutathione depletion can lead to multiple diseases, including neurodegenerative disorders (Alzheimers, Parkinsons), pulmonary disease (asthma, COPD), immune disease (HIV, autoimmune disease), cardiovascular diseases (hypertensions), liver disease, cystic fibrosis, and aging

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However, purified gB, when removed from the membrane or when omitting the transmembrane regions in ectodomain constructs, results in gB irreversibly adopting the postfusion conformation and thus unable to elicit prefusion-specific nanobodies

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Glutathione deficiency in Parkinsons disease: intranasal administration as a method of augmentation