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Your diarrhea risk with retatrutide may be lower than someone starting fresh, but the glucagon receptor activation is new territory for your gut

This article summarises the position reached with the GLP-1 RAs and reviews the developing field of unimolecular co-agonists that act not only on the GLP-1 receptor, but on other receptors, notably glucose-dependent insulotropic polypeptide (GIP) and glucagon receptors, with the aim of further improving glycaemic control and weight reduction

As a once-weekly injection, Ozempic belongs to a class of drugs called glucagon-like peptide 1 (GLP-1) receptor agonists and helps lower blood sugars by boosting insulin levels and lowering glucagon (a hormone that signals your liver to make glucose)

We are proud to continue advancing innovations that will have a meaningful impact for this patient population, underscoring Novo Nordisks commitment to cardiometabolic care. The FDA approval is based on results from the FLOW phase 3b kidney outcomes trial investigating the effects of once-weekly Ozempic injection on major kidney and cardiovascular outcomes in adults with type 2 diabetes and CKD

Cagrilintide, an amylin analog, is being studied both alone and in combination with semaglutide

Some evidence also suggests GLP-1 medications may help lower the risk of heart attacks and strokes in certain patients with obesity and heart disease