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This structural effect on neural architecture is what distinguishes Dihexa from most nootropics, which act primarily through neurotransmitter modulation

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549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons

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2013;4(5): e612