& Corvera, S
Potential Side Effects and Safety Any new treatment comes with questions about safety, and its smart to be informed
It is an essential cofactor for many enzymes which require thiol-reducing equivalents, and helps to keep redox-sensitive active sites on enzymes in the necessary reduced state
This is particularly relevant when we consider GSH pathways, as well as their transcriptional regulator Nrf2, for proliferation, survival and function of T cells, B cells and macrophages (325, 326)
Actives that disrupt the barrier, cause irritation, or cannot be used consistently tend to fail, not because they dont work, but because skin cant sustain them
Donnelly JG and Pronovost C (2000)