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doi: 10.1016/j.cell.2020.02.002 165 WanJLiuDPanSZhouSLiuZ

Alternatively, a pre-existing small population of open conformations can accommodate the peptide hormone smoothly and this may trigger the transition of GLP-1R from the closed to the otherwise energetically unfavorable open conformation (Fig

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I assume that the study is finished now